Neglected Tropical Diseases in HCS-Manguinhos

January 2023

Therapeutic Institute for Leprosy, Tocunduba, Belém, Brazil, ca. 1910. Wellcome Collection

Neglected tropical diseases (NTDs) are a diverse group of conditions that are mainly prevalent in tropical areas, where they mostly affect impoverished communities and disproportionately affect women and children. These diseases cause devastating health, social and economic consequences to more than one billion people.

The World Health Organisation formalized 30 January as World NTD Day every year to create better awareness on the devastating impact of NTDs on the poorest populations around the world. The epidemiology of NTDs is complex and often related to environmental conditions. Many of them are vector-borne, have animal reservoirs and are associated with complex life cycles. All these factors make their public-health control challenging.

Fiocruz is a reference center in the research and treatment of tropical diseases and Revista Historia Ciencias Saúde- Manguinhos, in its nearly 30 years of existence, has already published numerous articles on tropical diseases and on neglected ones.

We have selected articles, blog posts and stories that address, from a historical perspective, different topics related to tropical neglected diseases. Topics include different aspects of diseases such as leishmaniasis, leprosy (Hansen’s disease), Chagas disease, dengue, chikungunya and trachoma, and also health and prevention campaigns related to neglected tropical disease.

 The emergence of dengue as a virological challenge Although outbreaks were reported throughout the twentieth century, dengue was barely known in the Americas until the epidemic of dengue fever in Cuba in 1981.

Fiocruz carries out studies with mosquitoes to reduce transmission of dengue fever The Oswaldo Cruz Foundation (Fiocruz) has taken an important step into the project “Eliminate Dengue”, a natural method to block dengue virus transmission in Aedes aegypti.

Special issue on Chagas disease published in 2009.

Brazilian doctor appointed Assistant Director of PAHO Dr. Jarbas Barbosa da Silva Jr. received his medical degree from the Federal University of Pernambuco, Brazil, and specialized in public health and epidemiology at the National School of Public Health, Oswaldo Cruz Foundation (FIOCRUZ) in Rio de Janeiro. He will begin his five-year term on 1 February 2023.

Historical epidemiology in global health decision-making This article analyzes three examples of public health campaigns.

Chagas disease: science, health and society The year of 2019 marks 110 years of one of the great achievements in Brazilian science: the discovery, by Carlos Chagas, a young researcher at the Oswaldo Cruz Institute, of the disease that bears his name.

Trópicos, microbios y vectores El artículo analiza el modo como los investigadores argentinos y brasileños construyeron sus programas de investigación referidos a las enfermedades tropicales.

Leishmaniases from a historical and global perspective Brazil is the country in the Americas with the most cases of this disease in its three forms: cutaneous, mucocutaneous, and visceral.

International cooperation for equity in health This article analyzes the work of international organizations in health and the priorities of developing countries in this field since the 1990s.

‘Combating’ tropical diseases by the German language newspapers published in Brazil Article by Sílvio Marcus de Souza Correa

Health education posters used by the Department of Health and Public Assistance of Bahia State. In Education and health propaganda: repercussions of a Brazilian sanitarian’s training at the Rockefeller Foundation

Women made visible: the Institute of Tropical Medicine in Portugal This work in progress looks at the Institute’s scientific journal to identify the participation of women in tropical medicine between 1943 and 1966.

The Martsinovsky Institute of Medical Parasitology and Tropical Medicine in Moscow Tropical medicine emerged as a specialized field in Europe during the era of colonial expansion. Russia had no colonies in the tropics, but did possess vast territories with hot climates. This review presents the 100-year history of the Martsinovsky Institute of Medical Parasitology and Tropical Medicine in Moscow, Russia.

Historia de la enfermedad de Chagas en Argentina El artículo de Juan Pablo Zabala (Universidad Nacional de Quilmes/Conicet) presenta los puntos centrales de la trayectoria histórica de la enfermedad de Chagas en Argentina.

Chagas disease: science, health and society The year of 2019 marks 110 years of one of the great achievements in Brazilian science: the discovery, by Carlos Chagas, a young researcher at the Oswaldo Cruz Institute, of the disease that bears his name.

Chagas disease and tropical medicine in Brazil, 1908-1909 The disease was discovered in 1909 by the Brazilian sanitary physician Carlos Chagas at the Oswaldo Cruz Institute.

Carlos Chagas in the Amazon, 1913 It reviews the 21 days expedition up the Yaco River, in Alto Purus, federal territory of Acre.

Brazilian researchers have successfully tested a vaccine for Chagas disease Lab mice were observed after being infected with Chagas. While all animals that were not vaccinated died, 80% of those immunized survived.

Carlos Chagas (1879 – 1934), was a Brazilian sanitary physician, scientist and bacteriologist. He discovered Chagas disease in 1909, while working at the Oswaldo Cruz Institute in Rio de Janeiro.

Expert in Chagas disease dies at 93 Gastroenterologist Dr. Joffre Marcondes de Rezende contributed to medicine relating the Megaesophagus condition to Chagas disease.

Cattle trial cuts human sleeping sickness Cattle were given parasite-killing drug and area was sprayed with insecticide. This cut cases of human sleeping sickness by 90 per cent in Uganda

Health diplomacy in Africa It addresses regional dynamics in health diplomacy between 1920 and 1960. The article explores the alignments, divergences, and outcomes with respect to the strategies and policies pursued by colonial powers and independent African states.

“Colonies gave more than what they received in return” Rita Pemberton explains that although the colonies were rich in natural resources, this wealth was not reflected in the population’s health or sanitary conditions.

Wellcome Collection for Brazilian researchers See how to apply for a fellowship.

Railroads and tropical medicine in Brazil This paper by Jaime Benchimol and André Felipe Cândido da Silva, our former and current science editors, shows how railways supported the development of tropical medicine in the First Republic.

The tropics, science, and leishmaniasis The article investigates the process of circulation of knowledge which occurred during the first decades of the twentieth century between South American researchers and Europeans.

Health and development in Amazonas state This article shows that American cutaneous leishmaniasis emerged as a major health problem in Amazonas in close association with the political, economic, and socioenvironmental changes seen in the period.

Leishmaniases from a historical and global perspective Brazil is the country in the Americas with the most cases of this disease in its three forms: cutaneous, mucocutaneous, and visceral.

The establishment of the Manguinhos laboratory, 1894-1902 In order to understand the 1900 establishment of the Federal Serum Therapy Institute of Manguinhos, Rio de Janeiro, this paper analyzes the circulation of knowledge and international disputes surrounding vaccines.

Eradication efforts against global disease will be the focus of an exhibition Countdown to Zero, a new exhibition about scientific and social innovations that are ridding the world of ancient afflictions, will open at the American Museum of Natural History on January 13, 2015.

Chagas disease: science, health and society The year of 2019 marks 110 years of one of the great achievements in Brazilian science: the discovery, by Carlos Chagas, a young researcher at the Oswaldo Cruz Institute, of the disease that bears his name.

Chagas disease and tropical medicine in Brazil, 1908-1909 The disease was discovered in 1909 by the Brazilian sanitary physician Carlos Chagas at the Oswaldo Cruz Institute.

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